Tag Archives: Histones

Researchers show how a cancer gene protects genome organization

UNC study uncovers crucial function of a yeast enzyme Set2 whose well-conserved human counterpart is often mutated in cancers, especially kidney cancer. Media Contact: Mark Derewicz, 919-923-0959, mark.derewicz@unchealth.unc.edu June 13, 2017 CHAPEL HILL, NC – UNC School of Medicine researchers … Continue reading

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UNC Program in Chromatin and Epigenetics Launches

UNC has launched a new program that aims to address the fundamental gaps in knowledge surrounding epigenetic regulation, with a long-term goal of developing novel therapeutic approaches towards treating human disease. The program is centered around a highly collaborative and … Continue reading

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Epigenetic Breakthrough: A first of its kind tool to study the histone code

Scientists from UNC-Chapel Hill have created a new way to investigate epigenetic mechanisms important in diseases ranging from Alzheimer’s to cancers. Robert Duronio, PhD; Daniel McKay, PhD; Greg Matera, PhD; Brian Strahl, PhD. CHAPEL HILL, NC –University of North Carolina … Continue reading

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All the Cell’s a Stage

Brian Strahl, PhD, and his band of biochemists unravel the complicated mysteries of the epigenetic code to find a culprit in cancer development. By Mark Derewicz Every single human cell contains every single human gene.  But depending on the cell, … Continue reading

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Brian Strahl and colleagues identify another piece of the ‘histone code’ puzzle

UNC-CHAPEL HILL – DNA is often called the blueprint of life, but the four letter combinations that make up the genetic code are just part of the story.  Built upon the DNA lies additional ‘epigenetic’ information in the form of … Continue reading

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New research from the Strahl lab at UNC has established a link between histone H3 lysine 9 methylation and DNA methylation in humans

CHAPEL HILL, N.C. – Over the last two decades, scientists have come to understand that the genetic code held within DNA represents only part of the blueprint of life. The rest comes from specific patterns of chemical tags that overlay … Continue reading

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